Santa Ana, CA – Motorcycle Crash on I-5/Tustin Ranch Rd Leaves Rider Injured

Santa Ana, CA (November 19, 2025) – A major multi-vehicle collision involving a motorcycle on the southbound I-5 at Tustin Ranch Road left one rider with severe injuries late Tuesday, November 19. According to the California Highway Patrol, the crash involved at least three vehicles, including a black Honda Civic, a gray Toyota, and a gray Tesla that reportedly struck the motorcyclist. The impact caused the motorcycle to go down in the No. 2 lane, triggering an urgent medical response.

Fire personnel from Station 91 arrived quickly and provided on-scene treatment before the injured rider was transported to a nearby trauma center. Emergency workers assisted the victim and cleared debris. Several vehicles came to rest in the center divider, and an additional vehicle stopped to offer assistance.

The CHP is handling investigations into the crash.

We extend our sincere wishes for the rider’s full recovery.

If you or someone you love has suffered injuries in an I-5 motorcycle crash, call (888) 511-4558 to speak with our motorcycle accident lawyer for dedicated legal support.