Santa Ana, CA – Three-Vehicle Crash on I-5 S/SR-55 Leaves Several Injured

Santa Ana, CA (September 24, 2025) – Multiple injuries were reported on Wednesday evening, September 24, following a three-vehicle crash on I-5 southbound at the State Route 55 interchange in Santa Ana. The California Highway Patrol responded to the scene shortly after the collision, where three vehicles were involved in a chain-reaction crash. Several lanes were blocked, causing traffic delays during the busy evening commute.

Emergency medical teams evaluated those involved in the collision. At least one person sustained injuries serious enough to require transport to a nearby hospital, while others were treated on-site for injuries. Tow trucks arrived to remove the damaged vehicles, and the roadway was cleared later that evening. Authorities are investigating the cause of the crash and have not yet released further details on the victims.

Our hearts go out to those injured in this collision, and we wish them a speedy recovery.

Injured in a crash on I-5? Don’t wait to get the help you need to pursue compensation. Call (888) 511-4558 to speak with our skilled I-5 accident lawyers today.