Santa Ana, CA – Two-Vehicle Crash on I-5 at Main St. Leaves Victims Injured

Santa Ana, CA (August 26, 2025) – A two-vehicle collision on the northbound lanes of Interstate 5 near Main Street in Santa Ana left several people injured on Tuesday afternoon. The crash involved a black Jeep Cherokee and a white Kia SUV, both of which came to rest on the right shoulder following the impact. California Highway Patrol (CHP) officers arrived on scene shortly after the accident and confirmed that at least one person sustained injuries requiring medical evaluation.

Paramedics assessed victims at the scene before transporting them to a nearby hospital for further treatment. Officials reported visible damage to both vehicles, with airbags deployed in one of them. The collision temporarily slowed traffic through the busy corridor as authorities cleared debris and documented the scene. Investigators are still working to determine the cause of the crash.

Our thoughts are with those hurt in this collision, and we wish them a full and swift recovery.